Vol.37 No.4 2023
Cover story:
The cover depicts a tiny primate whose genetic makeup is an intricate mosaic crafted by human innovation. This chimeric monkey is the result of a meticulous biological choreography, where naive embryonic stem cells were precisely injected into an early-stage embryo, synchronized to the developmental rhythm to evade elimination. The chimera is more than a scientific curiosity: it stands to rewrite the playbook on modeling human diseases and therapeutic development.
To find more, please turn to page 210.
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- Contents
- 194 In This Issue
- 198 InBrief
- 200 CAS Research 2023 in Retrospect
- 210 Chimeric Monkeys: A Leap in Biomedical Science
- 213 Unlocking the Secrets of Heart Rejuvenation: The Promising Role of SIRT2
- 215 Unlocking the Brain's Gateway to Methamphetamine Addiction
- 217 Precision Gene Therapy Reverses Parkinson's Symptoms in Monkeys
- 220 Mapping the Developing Human Brain
- 223 Boosting Rice Yields in Acidic Soils through Microbial Allies
- 225 Seeing the Unseen
- 227 Safeguarding National Food Security by Coordinating Water and Land Resources with Environmental Governance
- 231 The Myth of Room Temperature Superconductivity in LK-99 Is Busted
- 232 Scientists Reveal the Band Topology and Orbital-selective Nematicity in a New Ti-based Kagome Superconductor
- 235 Tailoring Stable Chiral Materials Without Lead
- 236 New Strategy Boosting CO2 Reduction to CO
- 237 VMAT2 Transport and Inhibition Mechanisms Revealed by Cryo-EM
- 238 New Target for Delaying Primate Spinal Cord Aging
- 240 Novel Microbial Approach for Producing Carbohydrate-Derived Foods and Chemicals from LowCarbon Molecules
- 242 Novel Photoacoustic Imaging Guides Enhanced Photodynamic Therapy
- 243 Researchers Develop a Novel Drypowder Inhaled Vaccine Platform
- 245 Novel Intranasal Mask Provides Potent Protection against Viral Aerosols
- 247 Paleontologists Find New Fossil Link in Bird Evolution
- 250 The First Dinosaur Egg Was Leathery
- 252 Jawless "Bite" from the Past: Jurassic Fossils Shed Light on Lamprey Evolution
- 255 Fossils Show Ravens Lived Alongside Early Humans in Beijing